Larryn Peterson | Assistant Professor
Office: Kennedy 409 | | Email: petersonl@rhodes.edu

ShareThis
Translate


Education

Post-Doctoral Researcher, Stanford University
Ph.D. University of Southern California (Bioorganic Chemistry)
B.A. Carroll College (Chemistry)


Courses

Chemistry 211 - ORGANIC CHEMISTRY I
Chemistry 212 - ORGANIC CHEMISTRY II
Chemistry 212 - ORGANIC CHEMISTRY II LAB
Chemistry 451 - INTRODUCTION TO RESEARCH

 


Selected Publications

1.   L.W. Peterson, J.-S. Kim, S. Mitchell, P. Kijek, J.M. Breitenbach, K.Z. Borysko, J.C. Drach, J.M. Hilfinger, B.A. Kashemirov, C.E. McKenna. Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir. Bioorganic & Medicinal Chemistry Letters 2011, 21(13), 4045-4049. DOI:  10.1016/j.bmcl.2011.04126

2. V.M. Zakharova, M. Serpi, I.S. Krylov, L.W. Peterson, J.M. Breitenbach, K.Z. Borysko, J.C. Drach, M. Collins, J.M. Hilfinger, B.A. Kashemirov, C.E. McKenna. Tyr-based (S)-HPMPC and (S)-HPMPA prodrugs: Synthesis, stability, antiviral activity and in vivo transport studies. Journal of Medicinal Chemistry, 2011, 54(16), 5680-5693. DOI: 10.1021/jm2001426.

3. L.W. Peterson*, M. Sala-Rabanal*, I.S. Krylov, M. Serpi, B.A. Kashemirov, C.E. McKenna. Serine side chain-linked peptidomimetic prodrugs of cyclic cidofovir: Synthesis and interaction with hPEPT1. Molecular Pharmaceutics 2010, 7(6), 2349-2361. DOI: 10.1021/mp100186b

4. C.E. McKenna, B.A. Kashemirov, L.W. Peterson, M.F. Goodman. Modifications to the dNTP triphosphate moiety: From mechanistic probes for DNA polymerases to anti-viral and anti-cancer drug design. Biochimica et Biophysica Acta-Proteins and Proteomics 2010, 1804(5), 1223-1230.  DOI: 10.1016/j.bbapap.2010.01.005

5.  U. Tehler, C.S. Hartz, L.W. Peterson, C.J. Provoda, J.M. Hilfinger, K.-D. Lee, C.E. McKenna, G.L. Amidon. Puromycin-sensitive aminopeptidase (PSA): An antiviral prodrug activating enzyme. Antiviral Research 2010, 85(3), 482-489. DOI: 10.1016/j.antiviral.2009.12.003

6.  L.W. Peterson and C.E. McKenna. Prodrug approaches to improving the oral absorption of antiviral nucleotide analogues. Expert Opinion on Drug Delivery 2009, 6(3), 405-420. DOI: 10.1517/17425240902824808

7.  U. Eriksson, L.W. Peterson, B.A. Kashemirov, J.M. Hilfinger, J.C. Drach, K. Borysko, J. Breitenbach, J.-S. Kim, S. Mitchell, P. Kijek, C.E. McKenna. Serine peptide phosphoester prodrugs of cyclic cidofovir:  synthesis, transport and antiviral activity. Molecular Pharmaceutics 2008, 5(4), 598-609. DOI: 10.1021/mp8000099